Multi-Component Mechanism of H2 Relaxin Binding to RXFP1 through NanoBRET Kinetic Analysis

BL Hoare; S Bruell; A Sethi; PR Gooley; MJ Lew; MA Hossain; A Inoue; DJ Scott; RAD Bathgate

Journal article

Multi-Component Mechanism of H2 Relaxin Binding to RXFP1 through NanoBRET Kinetic Analysis

BL Hoare, S Bruell, A Sethi, PR Gooley, MJ Lew, MA Hossain, A Inoue, DJ Scott, RAD Bathgate

Iscience | CELL PRESS | Published : 2019

DOI: 10.1016/j.isci.2018.12.004

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Abstract

Biochemical Assay; Biological Sciences; Molecular Biology

University of Melbourne Researchers

Ashish Sethi Author

Paul Gooley Author

Akhter Hossain Author

Daniel Scott Author

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Grants

Awarded by Japan Agency for Medical Research and Development

Funding Acknowledgements

This research was supported by National Health and Medical Research Council of Australia project grants 1100676 and 1043750 (R.A.D.B., P.R.G., and D.J.S.) and the Victorian Government Operational Infrastructure Support Program. A.I. was funded by Japan Agency for Medical Research and Development (AMED) grant number JP17gm5910013 and Japan Society for the Promotion of Science (JSPS) KAKENHI grant number 17K08264. R.A.D.B. is supported by an NHMRC Research Fellowship, and D.J.S. is supported by an NHMRC Dementia Fellowship. The authors thank Tania Ferraro and Sharon Layfield for technical assistance.